Dapoxetine is a fast-acting SSRI used to treat premature ejaculation (PE). Unlike regular antidepressant SSRIs, it’s taken only when needed — usually 1–3 hours before sex. If you’re worried about quick ejaculation and want a straightforward, on-demand option, dapoxetine is the medicine most doctors will mention first.
This page gives clear, no-nonsense facts: how to take it, common side effects, safety checks, and practical alternatives you can discuss with your clinician.
Typical starting dose is 30 mg taken 1–3 hours before sex. If 30 mg doesn’t help and you tolerate it well, doctors may increase it to 60 mg. Don’t take more than one dose in 24 hours. Take it with water; food can delay absorption a bit, but it won’t stop it from working.
Most people only get mild side effects: nausea, dizziness, headache, or diarrhea. A small number feel faint or very sleepy, especially if mixed with alcohol. If you have heart problems, low blood pressure, or a history of fainting, tell your doctor — dapoxetine can affect heart rhythm in rare cases.
Important drug interactions: avoid dapoxetine with MAO inhibitors, other SSRIs or SNRIs, thioridazine, and drugs that strongly inhibit CYP3A4 (like some antifungals and HIV meds). Combining with alcohol raises the risk of fainting and dizziness. Women and boys under 18 generally should not use dapoxetine.
If you have moderate or severe liver problems, dapoxetine may not be safe. Always share your full medication list — even over-the-counter stuff — before starting dapoxetine.
If you feel a rapid heartbeat, severe dizziness, fainting, or blackouts after taking dapoxetine, stop taking it and seek medical help right away.
Not every option fits everyone. If dapoxetine isn’t right for you, there are alternatives: behavioral therapy, pelvic floor exercises, topical anesthetics (numbing creams), and other medications used off-label such as daily SSRIs or short-term tramadol in select cases. Our article "10 Alternatives to Priligy" lists practical choices and pros and cons — check it if you want options beyond dapoxetine.
Want a quick checklist before you try dapoxetine? 1) Confirm no major heart or liver issues, 2) avoid combining with certain meds and alcohol, 3) start at 30 mg and monitor side effects, 4) talk to your doctor about other options if it doesn’t help. If you need more details about dosing, safety, or alternatives, CanadianPharmacyService.com has plain-language guides and related posts to help you decide.
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